PDBe 1pvd

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF THE THIAMIN DIPHOSPHATE DEPENDENT ENZYME PYRUVATE DECARBOXYLASE FROM THE YEAST SACCHAROMYCES CEREVISIAE AT 2.3 ANGSTROMS RESOLUTION

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyruvate decarboxylase isozyme 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 555 amino acids
Theoretical weight: 60.74 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P06169 (Residues: 2-556; Coverage: 99%)
Gene names: L2104, PDC1, YLR044C
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand TPP 2 x TPP
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 142.06Å b: 74.75Å c: 120.32Å
α: 90° β: 116.58° γ: 90°
R-values:
R R work R free
0.165 0.165 not available
Expression system: Not provided