PDBe 1pl8

X-ray diffraction
1.9Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorbitol dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 356 amino acids
Theoretical weight: 38.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q00796 (Residues: 2-357; Coverage: 100%)
  • Best match: Q00796-2 (Residues: 2-89)
Gene name: SORD
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 4 x NAD
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P62
Unit cell:
a: 133.776Å b: 133.776Å c: 224.708Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.195 0.222
Expression system: Escherichia coli BL21(DE3)