PDBe 1pbw

X-ray diffraction
2Å resolution

STRUCTURE OF BCR-HOMOLOGY (BH) DOMAIN

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit alpha Chains: A, B
Molecule details ›
Chains: A, B
Length: 216 amino acids
Theoretical weight: 24.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P27986 (Residues: 105-319; Coverage: 30%)
Gene names: GRB1, PIK3R1
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 39.051Å b: 90.513Å c: 69.28Å
α: 90° β: 97.19° γ: 90°
R-values:
R R work R free
0.184 0.184 0.235
Expression system: Escherichia coli