PDBe 1p49

X-ray diffraction
2.6Å resolution

Structure of Human Placental Estrone/DHEA Sulfatase


Function and Biology Details

Reaction catalysed:
3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H(2)O = 3-beta-hydroxyandrost-5-en-17-one + sulfate
Biochemical function:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Entry contents:
1 distinct polypeptide molecule
Steryl-sulfatase Chain: A
Molecule details ›
Chain: A
Length: 562 amino acids
Theoretical weight: 63.05 KDa
Source organism: Homo sapiens
  • Canonical: P08842 (Residues: 22-583; Coverage: 100%)
Gene names: ARSC1, STS
Sequence domains:
Structure domains:

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P321
Unit cell:
a: 116.98Å b: 116.98Å c: 102.66Å
α: 90° β: 90° γ: 120°
R R work R free
0.254 0.254 0.301