PDBe 1ozt

X-ray diffraction
2.5Å resolution

Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Superoxide dismutase [Cu-Zn] Chains: G, H, I, J, K, L, M, N
Molecule details ›
Chains: G, H, I, J, K, L, M, N
Length: 153 amino acids
Theoretical weight: 15.85 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P21
Unit cell:
a: 79.617Å b: 69.998Å c: 113.787Å
α: 90° β: 110.37° γ: 90°
R R work R free
0.224 0.222 0.27
Expression system: Spodoptera frugiperda