PDBe 1oy2

Solution NMR

Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SHC-transforming protein 1 Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 22.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29353 (Residues: 111-317; Coverage: 36%)
Gene names: SHC, SHC1, SHCA
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamics
Expression system: Escherichia coli BL21(DE3)