PDBe 1ox7

X-ray diffraction
1.43Å resolution

Crystal structure of yeast cytosine deaminase apo-enzyme: inorganic zinc bound


Function and Biology Details

Reaction catalysed:
Cytosine + H(2)O = uracil + NH(3)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Cytosine deaminase Chains: A, B
Molecule details ›
Chains: A, B
Length: 161 amino acids
Theoretical weight: 18.09 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
  • Canonical: Q12178 (Residues: 1-158; Coverage: 100%)
Gene names: FCY1, YP9499.17, YPR062W
Sequence domains: Cytidine and deoxycytidylate deaminase zinc-binding region
Structure domains: Cytidine Deaminase, domain 2

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 54.491Å b: 70.467Å c: 71.941Å
α: 90° β: 90° γ: 90°
R R work R free
0.163 0.163 0.179
Expression system: Escherichia coli