PDBe 1oth

X-ray diffraction
1.85Å resolution

CRYSTAL STRUCTURE OF HUMAN ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH N-PHOSPHONACETYL-L-ORNITHINE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ornithine carbamoyltransferase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 36.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00480 (Residues: 34-354; Coverage: 91%)
Gene name: OTC
Sequence domains:
Structure domains: Aspartate/ornithine carbamoyltransferase

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P213
Unit cell:
a: 125.9Å b: 125.9Å c: 125.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.179 0.201
Expression system: Escherichia coli