PDBe 1oj5

X-ray diffraction
2.21Å resolution

Crystal structure of the Nco-A1 PAS-B domain bound to the STAT6 transactivation domain LXXLL motif

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor coactivator 1 Chain: A
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 14.81 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: P70365 (Residues: 256-385)
Gene names: Ncoa1, Src1
Signal transducer and activator of transcription 6 Chain: B
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.61 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Best match: P42226 (Residues: 795-808)
Gene name: STAT6

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS M18X
Spacegroup: P62
Unit cell:
a: 62.1Å b: 62.1Å c: 73.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.17 0.166 0.214
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided