PDBe 1oez

X-ray diffraction
2.15Å resolution

Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase

Released:

Function and Biology Details

Reaction catalysed:
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chains: W, X, Y, Z
Molecule details ›
Chains: W, X, Y, Z
Length: 153 amino acids
Theoretical weight: 15.85 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P41212
Unit cell:
a: 190.812Å b: 190.812Å c: 34.666Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.234
Expression system: Saccharomyces cerevisiae