PDBe 1obb

X-ray diffraction
1.9Å resolution

alpha-glucosidase A, AglA, from Thermotoga maritima in complex with maltose and NAD+


Function and Biology Details

Reaction catalysed:
Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Alpha-glucosidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 480 amino acids
Theoretical weight: 55.15 KDa
Source organism: Thermotoga maritima MSB8
Expression system: Escherichia coli
  • Canonical: O33830 (Residues: 1-480; Coverage: 100%)
Gene names: TM_1834, aglA
Sequence domains:
Structure domains: AglA-like glucosidase

Ligands and Environments

Cofactor: Ligand NAD 2 x NAD
1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR571
Spacegroup: P21
Unit cell:
a: 75Å b: 85.7Å c: 83.6Å
α: 90° β: 106° γ: 90°
R R work R free
0.199 0.199 0.235
Expression system: Escherichia coli