PDBe 1o1o

X-ray diffraction
1.8Å resolution

Deoxy hemoglobin (A,C:V1M,V62L; B,D:V1M,V67L)

Released:
Source organism: Homo sapiens
Primary publication:
Genetically Crosslinked Hemoglobin: A Structural Study
Acta Crystallogr. D Biol. Crystallogr. 56 812-816 (2000)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit beta Chains: B, D
Molecule details ›
Chains: B, D
Length: 146 amino acids
Theoretical weight: 15.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P68871 (Residues: 2-147)
Gene name: HBB
Hemoglobin subunit alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 141 amino acids
Theoretical weight: 15.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P69905 (Residues: 2-142)
Gene names: HBA1, HBA2

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: P21
Unit cell:
a: 63.094Å b: 83.218Å c: 53.655Å
α: 90° β: 99.29° γ: 90°
R-values:
R R work R free
0.181 not available 0.222
Expression system: Escherichia coli