PDBe 1nuh

X-ray diffraction
2.51Å resolution

The crystal structure of human phosphoglucose isomerase complexed with 5-phosphoarabinonate

Released:
Source organism: Homo sapiens
Primary publication:
The structure of human phosphoglucose isomerase complexed with a transition-state analogue.
Acta Crystallogr. D Biol. Crystallogr. 59 1111-3 (2003)
PMID: 12777791

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chain: A
Molecule details ›
Chain: A
Length: 558 amino acids
Theoretical weight: 63.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P06744 (Residues: 1-558; Coverage: 100%)
Gene name: GPI
Sequence domains: Phosphoglucose isomerase
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P43212
Unit cell:
a: 94.4Å b: 94.4Å c: 137.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.214 0.268
Expression system: Escherichia coli BL21