PDBe 1nt3

X-ray diffraction
2.4Å resolution

HUMAN NEUROTROPHIN-3

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurotrophin-3 Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20783 (Residues: 139-257; Coverage: 50%)
Gene name: NTF3
Sequence domains: Nerve growth factor family
Structure domains: Cystine-knot cytokines

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21212
Unit cell:
a: 37.434Å b: 52.067Å c: 64.795Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.263
Expression system: Escherichia coli