PDBe 1nl2

X-ray diffraction
2.3Å resolution

BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM AND LYSOPHOSPHOTIDYLSERINE

Released:

Function and Biology Details

Reaction catalysed:
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Activation peptide fragment 1 Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 16.86 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00735 (Residues: 44-189; Coverage: 24%)
Gene name: F2
Sequence domains:
Structure domains: Plasminogen Kringle 4

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 38.894Å b: 53.217Å c: 128.959Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.236 0.274