PDBe 1n25

X-ray diffraction
2.8Å resolution

Crystal structure of the SV40 Large T antigen helicase domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Large T antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 368 amino acids
Theoretical weight: 42.5 KDa
Source organism: Macaca mulatta polyomavirus 1
Expression system: Escherichia coli
UniProt:
  • Best match: P03070 (Residues: 260-627)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P321
Unit cell:
a: 120.321Å b: 120.321Å c: 132.202Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.243 0.243 0.276
Expression system: Escherichia coli