PDBe 1li1

X-ray diffraction
1.9Å resolution

The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Arresten Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 229 amino acids
Theoretical weight: 25.36 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02462 (Residues: 1441-1669; Coverage: 14%)
Gene name: COL4A1
Sequence domains: C-terminal tandem repeated domain in type 4 procollagen
Structure domains: Collagen IV, non-collagenous
Canstatin Chains: C, F
Molecule details ›
Chains: C, F
Length: 228 amino acids
Theoretical weight: 25.11 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08572 (Residues: 1485-1712; Coverage: 14%)
Gene name: COL4A2
Sequence domains: C-terminal tandem repeated domain in type 4 procollagen
Structure domains: Collagen IV, non-collagenous

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: R3
Unit cell:
a: 234.589Å b: 234.589Å c: 99.492Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.182 0.202