PDBe 1le2

X-ray diffraction
3Å resolution

STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apolipoprotein E Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.69 KDa
Source organism: Homo sapiens
Expression system: unidentified
UniProt:
  • Canonical: NEW P02649 (Residues: 41-184; Coverage: 48%)
Gene name: APOE
Structure domains: Apolipoprotein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 41.06Å b: 53.94Å c: 83.91Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.195 not available
Expression system: unidentified