PDBe 1lb4

X-ray diffraction
2.4Å resolution

TRAF6 apo structure


Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
TNF receptor-associated factor 6 Chain: A
Molecule details ›
Chain: A
Length: 159 amino acids
Theoretical weight: 18.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: NEW Q9Y4K3 (Residues: 348-504; Coverage: 30%)
Gene names: RNF85, TRAF6
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P21
Unit cell:
a: 32.183Å b: 55.581Å c: 47.709Å
α: 90° β: 100.97° γ: 90°
R R work R free
0.204 0.204 0.274
Expression system: Escherichia coli