PDBe 1krm

X-ray diffraction
2.5Å resolution

Crystal structure of bovine adenosine deaminase complexed with 6-hydroxyl-1,6-dihydropurine riboside

Released:
Source organism: Bos taurus
Primary publication:
Structure of bovine adenosine deaminase complexed with 6-hydroxy-1,6-dihydropurine riboside.
Acta Crystallogr. D Biol. Crystallogr. 59 299-303 (2003)
PMID: 12554940

Function and Biology Details

Reaction catalysed:
Adenosine + H(2)O = inosine + NH(3)
Biochemical function:
Biological process:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine deaminase Chain: A
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 40.33 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P56658 (Residues: 2-357; Coverage: 98%)
Gene name: ADA
Sequence domains: Adenosine/AMP deaminase
Structure domains: Metal-dependent hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P43212
Unit cell:
a: 80.03Å b: 80.03Å c: 141.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.198