PDBe 1kbh

Solution NMR

Mutual Synergistic Folding in the Interaction Between Nuclear Receptor Coactivators CBP and ACTR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor coactivator 3 Chain: A
Molecule details ›
Chain: A
Length: 47 amino acids
Theoretical weight: 5.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y6Q9 (Residues: 1045-1091; Coverage: 3%)
Gene names: AIB1, BHLHE42, NCOA3, RAC3, TRAM1
Structure domains: Nuclear receptor coactivator, Ncoa-type, interlocking domain
CREB-binding protein Chain: B
Molecule details ›
Chain: B
Length: 59 amino acids
Theoretical weight: 6.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P45481 (Residues: 2059-2117; Coverage: 2%)
Gene names: Cbp, Crebbp
Structure domains: Nuclear receptor coactivator, CREB-bp-like, interlocking domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Dyana, Sane, Amber
Expression system: Escherichia coli