PDBe 1k4q

X-ray diffraction
1.9Å resolution

Human Glutathione Reductase Inactivated by Peroxynitrite


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glutathione reductase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 461 amino acids
Theoretical weight: 50.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P00390 (Residues: 62-522; Coverage: 88%)
Gene names: GLUR, GRD1, GSR
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand FAD 1 x FAD
No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 119.75Å b: 63.65Å c: 84.71Å
α: 90° β: 58.42° γ: 90°
R R work R free
0.166 0.166 0.204
Expression system: Escherichia coli