PDBe 1jl9

X-ray diffraction
3Å resolution

Crystal Structure of Human Epidermal Growth Factor

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of human epidermal growth factor and its dimerization.
J. Biol. Chem. 276 34913-7 (2001)
PMID: 11438527

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 51 amino acids
Theoretical weight: 5.96 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P01133 (Residues: 971-1021; Coverage: 4%)
Gene name: EGF
Sequence domains: EGF-like domain
Structure domains: Laminin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3121
Unit cell:
a: 61.43Å b: 61.43Å c: 87.04Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.231 0.283
Expression system: Saccharomyces cerevisiae