PDBe 1j7w

X-ray diffraction
2Å resolution

Crystal structure of deoxy HbbetaYQ, a site directed mutant of HbA

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 141 amino acids
Theoretical weight: 15.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P69905 (Residues: 2-142)
Gene names: HBA1, HBA2
Hemoglobin subunit beta Chains: B, D
Molecule details ›
Chains: B, D
Length: 146 amino acids
Theoretical weight: 15.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P68871 (Residues: 2-147)
Gene name: HBB

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 63.36Å b: 84.32Å c: 54Å
α: 90° β: 99.43° γ: 90°
R-values:
R R work R free
0.181 0.181 0.223
Expression system: Escherichia coli