PDBe 1j2f

X-ray diffraction
2.3Å resolution

X-ray crystal structure of IRF-3 and its functional implications

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon regulatory factor 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 258 amino acids
Theoretical weight: 28.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW Q14653 (Residues: 175-427; Coverage: 59%)
Gene name: IRF3
Sequence domains: Interferon-regulatory factor 3
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P4212
Unit cell:
a: 134.808Å b: 134.808Å c: 69.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.217 0.242
Expression system: Escherichia coli