PDBe 1isf

X-ray diffraction
2.5Å resolution

Crystal Structure Analysis of BST-1/CD157

Released:

Function and Biology Details

Reaction catalysed:
(1a) NAD(+) = cyclic ADP-ribose + nicotinamide
Biochemical function:
Cellular component:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 265 amino acids
Theoretical weight: 30.17 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q10588 (Residues: 33-297; Coverage: 91%)
Gene name: BST1
Sequence domains: ADP-ribosyl cyclase
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6B
Spacegroup: P212121
Unit cell:
a: 58.721Å b: 112.612Å c: 130.086Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.213 0.25
Expression system: Trichoplusia ni