PDBe 1iri

X-ray diffraction
2.4Å resolution

Crystal structure of human autocrine motility factor complexed with an inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 558 amino acids
Theoretical weight: 63.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06744 (Residues: 1-558; Coverage: 100%)
Gene name: GPI
Sequence domains: Phosphoglucose isomerase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P212121
Unit cell:
a: 80.651Å b: 107.771Å c: 270.345Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.241
Expression system: Escherichia coli