PDBe 1iqf

X-ray diffraction
3.2Å resolution

Human coagulation factor Xa in complex with M55165

Released:
Source organism: Homo sapiens
Entry authors: Shiromizu I, Matsusue T

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Activated factor Xa heavy chain Chain: A
Molecule details ›
Chain: A
Length: 235 amino acids
Theoretical weight: 26.6 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00742 (Residues: 235-469; Coverage: 51%)
Gene name: F10
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Factor X light chain Chain: L
Molecule details ›
Chain: L
Length: 96 amino acids
Theoretical weight: 10.53 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00742 (Residues: 84-179; Coverage: 21%)
Gene name: F10
Sequence domains:
Structure domains: Laminin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 72.29Å b: 78.04Å c: 56.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.169 0.277