PDBe 1igw

X-ray diffraction
2.1Å resolution

Crystal Structure of the Isocitrate Lyase from the A219C mutant of Escherichia coli

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Isocitrate lyase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 434 amino acids
Theoretical weight: 47.6 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A9G6 (Residues: 1-434; Coverage: 100%)
Gene names: JW3975, aceA, b4015, icl
Sequence domains: Isocitrate lyase family
Structure domains: Phosphoenolpyruvate-binding domains

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: P32
Unit cell:
a: 88.65Å b: 88.65Å c: 199.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.184 0.235
Expression system: Escherichia coli