PDBe 1ibr

X-ray diffraction
2.3Å resolution

COMPLEX OF RAN WITH IMPORTIN BETA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GTP-binding nuclear protein Ran Chains: A, C
Molecule details ›
Chains: A, C
Length: 216 amino acids
Theoretical weight: 24.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62826 (Residues: 1-216; Coverage: 100%)
Gene names: ARA24, OK/SW-cl.81, RAN
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Importin subunit beta-1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 462 amino acids
Theoretical weight: 51.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q14974 (Residues: 1-462; Coverage: 53%)
Gene names: KPNB1, NTF97
Sequence domains:
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P21
Unit cell:
a: 65.7Å b: 108.95Å c: 114.05Å
α: 90° β: 100.66° γ: 90°
R-values:
R R work R free
0.245 0.245 0.272
Expression system: Escherichia coli BL21(DE3)