PDBe 1hsb

X-ray diffraction
1.9Å resolution

DIFFERENT LENGTH PEPTIDES BIND TO HLA-AW68 SIMILARLY AT THEIR ENDS BUT BULGE OUT IN THE MIDDLE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A-68 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 270 amino acids
Theoretical weight: 31.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01891 (Residues: 25-294; Coverage: 79%)
Gene names: HLA-A, HLAA
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
BOUND PEPTIDE FRAGMENT Chain: C
Molecule details ›
Chain: C
Length: 3 amino acids
Theoretical weight: 259 Da

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 59.43Å b: 78.469Å c: 111.904Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.22 not available