PDBe 1hs5

Solution NMR

NMR SOLUTION STRUCTURE OF DESIGNED P53 DIMER

Released:
Source organism: Homo sapiens
Primary publication:
Structure and functionality of a designed p53 dimer.
J. Mol. Biol. 307 605-17 (2001)
PMID: 11254385

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chains: A, B
Molecule details ›
Chains: A, B
Length: 34 amino acids
Theoretical weight: 4.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04637 (Residues: 324-357; Coverage: 9%)
  • Best match: P04637-8 (Residues: 192-199)
Gene names: P53, TP53

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli