PDBe 1hla

X-ray diffraction
3.5Å resolution

STRUCTURE OF THE HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN, HLA-A2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
HLA class I histocompatibility antigen, A-2 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 270 amino acids
Theoretical weight: 31.17 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01892 (Residues: 25-294; Coverage: 79%)
Gene names: HLA-A, HLAA
Sequence domains:
Beta-2-microglobulin Chain: M
Molecule details ›
Chain: M
Length: 97 amino acids
Theoretical weight: 11.5 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P61769 (Residues: 21-117; Coverage: 98%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 60.2Å b: 80.4Å c: 112.2Å
α: 90° β: 90° γ: 90°
Expression system: Not provided