PDBe 1h2c

X-ray diffraction
1.6Å resolution

Ebola virus matrix protein VP40 N-terminal domain in complex with RNA (High-resolution VP40[55-194] variant).

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 16-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Matrix protein VP40 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 15.32 KDa
Source organism: Ebola virus sp.
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05128 (Residues: 55-194; Coverage: 43%)
Gene name: VP40
Structure domains: Topoisomerase I; domain 3
5'-R(*UP*GP*AP)-3' Chain: R
Molecule details ›
Chain: R
Length: 3 nucleotides
Theoretical weight: 936 Da
Source organism: Escherichia coli

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P422
Unit cell:
a: 80.51Å b: 80.51Å c: 46.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.164 0.182
Expression system: Escherichia coli