1g7a

X-ray diffraction
1.2Å resolution

1.2 A structure of T3R3 human insulin at 100 K

Released:
Source organism: Homo sapiens
Primary publication:
Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced?
Acta Crystallogr D Biol Crystallogr 57 1091-100 (2001)
PMID: 11468392

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134235 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
Insulin B chain Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 25-54; Coverage: 35%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: R3
Unit cell:
a: 80.127Å b: 80.127Å c: 71.582Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.169 0.169 0.193
Expression system: Not provided