PDBe 1fzf

X-ray diffraction
2.7Å resolution

CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Fibrinogen alpha chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 87 amino acids
Theoretical weight: 10.24 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02671 (Residues: 130-216; Coverage: 10%)
Gene name: FGA
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Fibrinogen beta chain Chains: B, E
Molecule details ›
Chains: B, E
Length: 328 amino acids
Theoretical weight: 37.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02675 (Residues: 164-491; Coverage: 71%)
Gene name: FGB
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Structure domains:
Fibrinogen gamma chain Chains: C, F
Molecule details ›
Chains: C, F
Length: 319 amino acids
Theoretical weight: 36.22 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02679 (Residues: 114-432; Coverage: 75%)
Gene names: FGG, PRO2061
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Structure domains:
Fibrinogen beta chain Chains: M, N, S, T
Molecule details ›
Chains: M, N, S, T
Length: 4 amino acids
Theoretical weight: 468 Da
Source organism: Homo sapiens
UniProt:
  • Canonical: P02675 (Residues: 45-48; Coverage: 1%)
Gene name: FGB

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 54.8Å b: 149.4Å c: 234.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 0.302