PDBe 1fga

X-ray diffraction
2.2Å resolution

REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 2 Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 16.44 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09038 (Residues: 143-288; Coverage: 51%)
Gene names: FGF2, FGFB
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P1
Unit cell:
a: 30.8Å b: 33.5Å c: 35.8Å
α: 58.8° β: 72.4° γ: 76.1°
R-values:
R R work R free
0.138 not available not available
Expression system: Not provided