PDBe 1f76

X-ray diffraction
2.5Å resolution

ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydroorotate dehydrogenase (quinone) Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 336 amino acids
Theoretical weight: 37.15 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A7E1 (Residues: 1-336; Coverage: 100%)
Gene names: JW0928, b0945, pyrD
Sequence domains: Dihydroorotate dehydrogenase
Structure domains: Aldolase class I

Ligands and Environments


Cofactor: Ligand FMN 4 x FMN
2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P41212
Unit cell:
a: 119.7Å b: 119.7Å c: 295.97Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.177 0.217
Expression system: Escherichia coli