PDBe 1f59

X-ray diffraction
2.8Å resolution

IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit beta-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 442 amino acids
Theoretical weight: 49.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14974 (Residues: 1-442; Coverage: 51%)
  • Best match: Q14974-2 (Residues: 1-297)
Gene names: KPNB1, NTF97
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
FXFG NUCLEOPORIN REPEATS Chains: C, D
Molecule details ›
Chains: C, D
Length: 28 amino acids
Theoretical weight: 2.69 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21212
Unit cell:
a: 67.246Å b: 211.79Å c: 125.815Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.262
Expression system: Escherichia coli