PDBe 1ev3

X-ray diffraction
1.78Å resolution

Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer

Released:
Source organism: Homo sapiens
Primary publication:
R6 hexameric insulin complexed with m-cresol or resorcinol.
Acta Crystallogr. D Biol. Crystallogr. 56 1541-8 (2000)
PMID: 11092919

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero 12-mer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 90-110; Coverage: 24%)
Gene name: INS
Insulin B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 30 amino acids
Theoretical weight: 3.43 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 25-54; Coverage: 35%)
Gene name: INS

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: R3
Unit cell:
a: 78.866Å b: 78.866Å c: 39.465Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.2 0.266
Expression system: Not provided