PDBe 1euj

X-ray diffraction
1.8Å resolution

A NOVEL ANTI-TUMOR CYTOKINE CONTAINS A RNA-BINDING MOTIF PRESENT IN AMINOACYL-TRNA SYNTHETASES

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endothelial monocyte-activating polypeptide 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 166 amino acids
Theoretical weight: 18.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW Q12904 (Residues: 147-312; Coverage: 53%)
Gene names: AIMP1, EMAP2, SCYE1
Sequence domains: Putative tRNA binding domain
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 134.01Å b: 38.34Å c: 80.99Å
α: 90° β: 112.9° γ: 90°
R-values:
R R work R free
0.213 0.208 0.232
Expression system: Escherichia coli