PDBe 1eta

X-ray diffraction
1.7Å resolution

THE X-RAY CRYSTAL STRUCTURE REFINEMENTS OF NORMAL HUMAN TRANSTHYRETIN AND THE AMYLOIDOGENIC VAL 30-->MET VARIANT TO 1.7 ANGSTROMS RESOLUTION

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: 1, 2
Molecule details ›
Chains: 1, 2
Length: 127 amino acids
Theoretical weight: 13.81 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02766 (Residues: 21-147; Coverage: 100%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 43.64Å b: 86.18Å c: 65.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 not available not available
Expression system: Not provided