PDBe 1eku

X-ray diffraction
2.9Å resolution

CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon gamma Chains: A, B
Molecule details ›
Chains: A, B
Length: 265 amino acids
Theoretical weight: 31.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01579 (Residues: 24-144, 26-161; Coverage: 97%)
Gene name: IFNG
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: R32
Unit cell:
a: 111.38Å b: 111.38Å c: 311.96Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.246 0.265
Expression system: Escherichia coli