PDBe 1egc

X-ray diffraction
2.6Å resolution

STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 396 amino acids
Theoretical weight: 43.65 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P11310 (Residues: 26-421; Coverage: 94%)
Gene name: ACADM
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 4 x FAD
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 170Å b: 170Å c: 149.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.217 not available
Expression system: Not provided