PDBe 1ef7

X-ray diffraction
2.67Å resolution

Function and Biology Details

Reaction catalysed:
Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Cathepsin Z Chains: A, B
Molecule details ›
Chains: A, B
Length: 242 amino acids
Theoretical weight: 27.18 KDa
Source organism: Homo sapiens
  • Canonical: Q9UBR2 (Residues: 62-303; Coverage: 86%)
Gene name: CTSZ
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 62.251Å b: 92.48Å c: 209.876Å
α: 90° β: 90° γ: 90°
R R work R free
0.183 not available 0.226