PDBe 1e3f

X-ray diffraction
1.9Å resolution

Structure of human transthyretin complexed with bromophenols: a new mode of binding

Released:
Source organism: Homo sapiens
Primary publication:
Structure of human transthyretin complexed with bromophenols: a new mode of binding.
Acta Crystallogr. D Biol. Crystallogr. 56 1085-95 (2000)
PMID: 10957627

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 127 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02766 (Residues: 21-147; Coverage: 100%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P21212
Unit cell:
a: 42.7Å b: 85.4Å c: 64.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.252