PDBe 1dyt

X-ray diffraction
1.75Å resolution

X-ray crystal structure of ECP (RNase 3) at 1.75 A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eosinophil cationic protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 15.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12724 (Residues: 28-160; Coverage: 100%)
Gene names: ECP, RNASE3, RNS3
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P4322
Unit cell:
a: 62.163Å b: 62.163Å c: 174.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.271
Expression system: Escherichia coli BL21(DE3)