PDBe 1dk8

X-ray diffraction
1.57Å resolution

CRYSTAL STRUCTURE OF THE RGS-HOMOLOGOUS DOMAIN OF AXIN

Released:
Source organism: Homo sapiens
Primary publication:
Structural basis of the Axin-adenomatous polyposis coli interaction.
EMBO J. 19 2270-9 (2000)
PMID: 10811618

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Axin-1 Chain: A
Molecule details ›
Chain: A
Length: 147 amino acids
Theoretical weight: 16.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15169 (Residues: 74-220; Coverage: 17%)
Gene names: AXIN, AXIN1
Sequence domains: Regulator of G protein signaling domain
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: C2221
Unit cell:
a: 32.57Å b: 117.88Å c: 81.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.172 0.198
Expression system: Escherichia coli