PDBe 1dbh

X-ray diffraction
2.3Å resolution

DBL AND PLECKSTRIN HOMOLOGY DOMAINS FROM HSOS1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Son of sevenless homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 354 amino acids
Theoretical weight: 41.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q07889 (Residues: 198-551; Coverage: 27%)
Gene name: SOS1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: C2
Unit cell:
a: 104.4Å b: 70.44Å c: 73.83Å
α: 90° β: 96.29° γ: 90°
R-values:
R R work R free
0.229 0.229 0.269
Expression system: Escherichia coli BL21