PDBe 1d5x

X-ray diffraction
2.45Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Enterotoxin type B Chain: C
Molecule details ›
Chain: C
Length: 239 amino acids
Theoretical weight: 28.41 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: P01552 (Residues: 28-266; Coverage: 100%)
Gene name: entB
Sequence domains:
Structure domains:
DIPEPTIDE MIMETIC INHIBITOR Chain: D
Molecule details ›
Chain: D
Length: 6 amino acids
Theoretical weight: 741 Da
HLA class II histocompatibility antigen, DR alpha chain Chain: A
Molecule details ›
Chain: A
Length: 181 amino acids
Theoretical weight: 21.08 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P01903 (Residues: 26-206; Coverage: 79%)
Gene names: HLA-DRA, HLA-DRA1
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DRB1-4 beta chain Chain: B
Molecule details ›
Chain: B
Length: 192 amino acids
Theoretical weight: 22.52 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P13760 (Residues: 30-221; Coverage: 81%)
Gene name: HLA-DRB1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

3 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 90.838Å b: 104.252Å c: 107.818Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.237 0.268
Expression system: Drosophila melanogaster